Evaluation of Platelet Aggregation on Commonly-Used Blood-Contacting Medical Polymers
The blood compatibility of polymers used for medical devices which facilitate the movement or storage of blood is critical, particularly in devices whose applications where device-contacting blood will be re-introduced into a patient (dialyzer housings, storage vessels, IV components, etc.). Standard biocompatibility testing conducted in accordance with the ISO 10993 series of standards for these materials includes various tests for hemocompatibility1, including platelet interactions, but direct microscopic examination of platelet adhesion and activation is less common. This white paper presents the results of a scanning electron microscopic (SEM) examination of human platelet adhesion on polymeric materials, which shows that CYROLITE® materials may be less likely to aggregate and activate platelets than some other commonly-used blood-contacting materials.
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