What Causes Wrinkles in Heat-Sealed Pouches?
Wrinkles in the seal area can cause a package to be rejected. Let's look at somethings that can be done to avoid packaging failures.

Is Heatsealing Art or Science?
The evolution of heat sealing perfection from hot bars, to impulse to VRC TOSS Technology. Today's heat sealers provide much more than just sealing the pouches.  Advanced security, information downloading, recipe storage, easy validation.....  

The Real Story About Controlled Impulse Heat Sealing of Polymeric Materials
Toss VRC Technology is an improved method of impulse heat sealing that overcomes the limitations of simplistic convention methods. It brings advantages to the fabrication and packaging requirements of the Medical/Pharmaceutical/Healthcare and Biotech Industries. Advantages that are not available with oth

Avoid Pouch Sealing Disasters - The 9-Steps to Heat Sealing Perfection
Step 1 Heat Sealing Configuration. Determine what is expected from the seal. What does one expect from a heat seal? Wide, narrow, shaped, or just seal or seal and cut? Before a satisfactory sealing system can be designed it is necessary to decide what seal configuration is desired. Step 2 Heatseal Ban

Less is More: How Lean Processes can Bolster Profits and Sustainability
Medical device manufacturers are just like every other business regarding their desire to maximize profits and sustainability by reducing waste and losses. However, unlike most businesses, medical device manufacturers don’t use specific, proven methodologies to achieve these goals.

Going (Well) Beyond Product Safety Standards
Medical manufacturer GCX outlines safety tests that every hospital or medical device manufacturer should conduct before a solution is put into production.

How to Select a DC Motor: Coreless and Iron Core Brushed DC Motors
Considering a coreless DC motor for your next application? Can’t decide between brush and brushless? Despite their simplicity, selecting a small DC motor for an application can still be a daunting task. There are many other variables to take into account including dimensions, load, duty cycle, etc. This white

Calculations & Formulas for Brush DC Motors
When selecting a brush DC motor for an application or developing a powered prototype, there are several basic motor physics principles which must be considered to produce a safe, well-functioning, sufficiently-powered precision drive system. This guide includes important methods, formulas & calculation detail

Top 100 Medical Device Companies of 2019
See which companies lead the pack in the medtech industry with our free 2019 ranking of the top 100 public medical device and diagnostics companies by sales. Information in the report includes the following: Company name Exchange ticker Exchange 2019 revenue

Surgical Robotics: The Market Landscape Today and Tomorrow
Robotic surgery has been a reality since Intuitive Surgical came to market in 2000, but recent innovations are transforming the landscape significantly. Both startups and traditional medical device companies have introduced robotic approaches for a range of surgical procedures, while Intuitive has already

Motor Type Selection
Parameters that define a motor type are the mechanical output power, the shaft bearing system, the commutation systemused, and the possible combinations with gearheads and sensors. The most important criteria include the speed andtorque requirements, and the commutation system.

High Efficiency Motors
To understand the concept of high efficiency motors, you must first know how to calculate efficiency and the losses associated with the motor components themselves.

Finding the Optimal Metal Tubing for Medical and Critical Applications
Selecting the best alloy for a tubing application can be a daunting task considering the wide variety of stainless steel and metal alloys available. The chromium in stainless steel forms a coherent passive oxide film and oxygen barrier, which imparts corrosion resistance. All stainless steels contain at least

Simulation of Radiation Sterilization: Choosing the Best Packing Configuration
For cost reduction, it is beneficial to choose a packing configuration that allows for the highest throughput. Typically, the ideal arrangement is found through experimental trial-and-error. In addition to being expensive and time-consuming, such an approach might miss the packing configuration that finds the

Simulation of Radiation Sterilization: Guiding Product Design
In a typical product design process, testing to ensure that the sterilization regulations are met is only performed after the product has been fully designed, built, tested, and readied for mass production. There is an inherent risk to this approach: a great deal of effort and resources have been invested in

Simulation of Radiation Sterilization: Selection and Optimization of the Right Source
When using radiation sterilization, medical device and pharmaceutical companies are faced with the choiceof gamma, electron-beam, or x-ray sources. But which one to choose? While it may be tempting to go withthe familiar option, each of these techniques has its own benefits that might make it the ideal choice

Using Polyisoprene to Differentiate Your Medical Device
3 Key Takeaways for Engineers

Automated Pill Dispenser
An automated pill dispensing system manufacturer required a unique seal coupler design to enhance pill counting and dispensing functions. Minnesota Rubber and Plastics provided a new lip seal design solving the initial problem of seal alignment with a more precise fitting lip configuration at the seal end for

Needless Injector
Provide the complete assembly of 39 components for improved quality while streamlining the projects oversight responsibility. Eliminate the customer's management of multiple vendors supplying individual components. 

Check Valve Assembly
Topical oxygen therapy is used to treat patients with nonhealing wounds. A new topical oxygen system utilizes a unique check valve that stops the fl ow of oxygen out of the oxygen-enriched container if the patient disconnects it from the oxygen source. The relief valve maintains the infl ation pressure inside

Agile in an FDA Regulated Environment

Breakthrough Inline Measurement Technology for Silicone Tubing
In an industry first, Freudenberg Medical has developed a ground-breaking new technology to continuously measure the inner geometry of silicone tubes. This new measurement technology, called Helix iMC™, uses sensors to continuously measure the inner geometry of extruded products such as single- or multi-lumen

Compression Spring Basic Features
Lee Spring (celebrating 100 years in manufacturing) provides a basic overview of compression springs used in a wide variety of Applications, including medical devices. A compression spring is an open-coil helical spring that offers resistance to a compressive force applied axially. Compression Springs are th

Compression Spring Design and General Considerations
There are a number of design considerations when working with compression springs. Let us first consider stress, set and weight as important considerations in establishing a custom spring design which need to be understood at the outset. Download the Lee Spring (celebrating 100 years in manufacturing) white

Resorbable Polymer Implants: Attention to WIP Exposure
This white paper is meant to identify critical considerations related to WIP Exposure vulnerabilities of resorbable polymers. A structured and disciplined assessment of the different contributors to the Overall Exposure Risk will enable a fact based decision pathway that will result in the establishment of a

Metrics That Matter for Quality Manufacturing
How MasterControl Customers Measure the Impact of Manufacturing Excellence™.

The Clock Is Ticking: Will Notified Body Capacity for the EU MDR Affect You?
In July, we published a white paper on the progress of the new European Union Medical Device Regulation (MDR) and In Vitro Device Regulation (IVDR) and how the lack of Notified Bodies (NB) could affect timely implementation. The deadline is looming larger and some small progress has been made, along with some

The Essential Laser for Orthopedics
Ask any orthopedic surgeon to show you the tools of the trade, and the evidence of laser processing is not difficult to spot. Most devices and tools, even single-use items, bear the telltale traces of marking lasers used to indicate depth, part number, and lot or serial number. The growth of laser usage is

Crash Course: Heat Sealers and Sealer Validation
A collaboration between Packworld USA and Packaging Compliance Labs

Identification of Adhesive Formulations Minimally Effected by E-Beam Sterilization
A selection of medical/skin adhesives were coated onto substrates and physical properties (Shear, Adhesion to Release, 180° Peel and MVTR) tested before and after exposure to e-beam sterilization of 27 and 40 kGy. Of the four adhesives tested, two displayed a much lower effect from e-beam exposure than the ot