To explore the recent trends and the future direction for the development and commercialization of biomedical textiles in regenerative medicine, it is necessary to look at some areas in which their uses are expanding as well as an ongoing success story in which a material is moving from bench top to market. This paper reviews the use of biomedical textiles in light of the generational scheme of biomaterials, outlines crucial success factors for bringing projects out of university labs and into commercial use, and discusses how Secant Medical’s advanced biomaterial, Regenerez™, fits within this evolution.